Capacities

With the methodology developed by our group, we can become your research partner, analyzing samples from clinical studies and applying quantitative targeted metabolomics in the fields of precision medicine and nutrition.

Targeted and Quantitative Metabolomics

The biomarker panels developed by the group (Exposome-UB and Mega-UB) have been published in high-impact scientific journals and have been awarded by international societies.

Exposome Biomarker Panel

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Features of Exposome-UB:

  • Analysis of nearly 2,000 metabolites in a single measurement.
  • Tryptophan Metabolism
  • Isothiocyanates
  • Kynurenines
  • Glucosinolates
  • Flavonoids
  • Indole and Its Derivatives
  • Resorcinol and Its Derivatives
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Clinical Biomarker Panel

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MEGA-UB Features

  • Over 600 metabolites analyzed
  • More than 21 chemical families
  • Over 250 metabolite ratios
  • 173 isotopically labeled internal standards (ISTD) used
  • Validated for plasma, urine, and fecal extract
  • Requires only 100 microliters of sample volume
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EXPOSOME-UB Panel

This panel optimizes, validates, and applies a multi-metabolite platform for exposome research based on metabolomics.

This methodology stands out for its broad metabolome coverage and its applicability in fields such as health research, nutrimetabolomics, toxicometabolomics, and pharmacometabolomics.

Key features:

  • Simultaneous quantification of over 2,000 metabolites.
  • Applicable to urine, blood, plasma, and fecal samples.
  • Short analysis times.
  • Requires small sample volumes, enabling large-scale epidemiological studies.

 

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MEGA-UB Panel

 

The MEGA-UB panel enables the quantification and identification of novel biomarkers for cardiovascular disease, cognitive decline, metabolic disorders, and more.

Key Features:

  • Simultaneous quantification of over 600 metabolites.
  • Ensures precision in metabolite quantification.
  • Efficient and cost-effective for managing large sample volumes.
  • Broad metabolite coverage for essential clinical insights into health and disease.
  • Transformative development for precision diagnostics and therapeutic monitoring.

This panel has been validated in a clinical study focused on mild cognitive impairment, where it helped measure metabolic changes in response to a Mediterranean diet intervention (Zhang L, et al,. Metabolites. 2024).

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GIGA-UB Panel

The GIGA-UB panel is an advanced tool for metabolomic analysis of plasma, serum, urine, tissues, milk, cerebrospinal fluid, meat, cell media, cell lysates, and cells.

Key Features:

  • Up to 1,300+ metabolites.
  • Covers up to 27 chemical families, including microbial metabolites.
  • Chemical Families: Acylcarnitines, Amino acids, Biogenic amines, Cholesterol esters, and Diglycerides.
  • Metabolic Pathways: Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Lipid metabolism, Urea Cycle, Redox Balance, Cholesterol metabolism, Microbial metabolism.
  • Validated for plasma, urine, and fecal extracts.
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UB-PRIME PANEL

The UB-Prime panel enables the identification and quantification of 143 different metabolites commonly measured in biofluids and other sample matrices.

Key Features:

  • Up to 145 metabolites.
  • Covers up to 11 chemical families.
  • Chemical Classes: Lipids, Fatty acids, Amino acids, Organic acids, Biogenic amines, Acylcarnitines, Phosphatidylcholines, Lysophosphatidylcholines (LysoPCs), Sphingomyelins, Sugars, and Neurotransmitters.
  • Metabolic Pathways: Tricarboxylic acid cycle (Krebs cycle), Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Lipid metabolism, Urea cycle, Redox balance, and One-carbon metabolism.
  • Fully validated and optimized for plasma and urine samples.
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EXPOSURE PANEL

Targeted Quantitative Metabolomic Panel
Aimed at better characterizing the biological imprint of external agents, including environmental pollutants and contaminants. This panel enables targeted analysis of exposome-related metabolites in multiple biofluids using LC-MS.

Key Features:

  • Up to 115 metabolites.
  • Chemical Families: Amino acids, Organic acids, Biogenic amines, Vitamins, Metals, and Fatty acids.
  • Metabolic Pathways: Tricarboxylic acid cycle (TCA), Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Metal ion metabolism, and Cation metabolism.
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ADDITIONAL CAPACITIES

Data Analysis

In addition to metabolite quantification, we offer a dedicated data analysis service. By leveraging bioinformatics databases such as the Human Metabolome Database (HMDB) and the Small Molecule Pathway Database (SMPDB), along with the R-Commander tool, we provide comprehensive data interpretation.

We can assist you in analyzing your results to ensure your research benefits from all relevant information.

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Polyphenol Intake Assessment

Thanks to the research developed by the group and in collaboration with IDIBELL, we have developed a patented software tool for quantifying the total intake, classes, subclasses, and individual intake of dietary polyphenols.

The application is primarily designed for research studies requiring polyphenol intake quantification, but it is also useful for developing new products in the food industry, as well as for healthcare professionals who need to measure polyphenol intake in the diet.

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We have worked with the following national and international companies and institutions

How can we help you?

Fill out the form, and we will contact you to answer your inquiry.

Department of Nutrition, Food Science, and Gastronomy

Faculty of Pharmacy and Food Sciences, INSA-UB

University of Barcelona
Diagonal Campus, Avda. Joan XXIII, 27-31, Building B
08028 – Barcelona

Mail: grc.nutrimetabolomic@ub.edu


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